Important festivals in the province include the traditional dances of the Phu Thai ethnic group held during May and June every year. The Phra That Phanom temple fair is held every February, on which occasion many locals pilgrimate to the temple to pay homage. At the end of the Buddhist lent in November illuminated a boat procession is done.
The cuisine is mostly the same as in all Isan. Pla Ra, a kind of preserved fish, originally comes from the Si Songkhram area and is now popular in the whole country.
Traditional products in the province include hand-woven fabric, made from silk or cotton. Renu Nakhon, That Phanom and Si Songkhram districts are the center of this industry. Also hand-made Kaen instruments can be found in the province