The Kirillo-Belozersky Monastery, located in the town, is a fortified ensemble built in the 15th and the 16th centuries. It also hosts the Kirillo-Belozersky Museum of History, Art, and Architecture, an umbrella institution governing all museums of Kirillovsky District. The monastery has been designated as a cultural heritage monument of federal significance. Kirillov also preserved the historical center, and the town hosts 77 cultural heritage monuments. This number includes both the buildings in and outside the monastery.
Dmitry Grave, a Russian mathematician, was born in Kirillov in 1863, though he spent his career elsewhere
