lsion of the Ghibelline family of the Lambertazzi in 1274.
After this period of great prosperity, Bologna experienced some ups and downs: it was crushed in the Battle of Zappolino by the Modenese in 1325 but then prospered under the rule of Taddeo Pepoli (1337–1347). Then in 1348, during the Black Plague, about 30,000 inhabitants died, and it subsequently fell to the Visconti of Milan, but returned to Papal control under Cardinal Gil de Albornoz in 1360. In the following years, Republican governments like that of 1377, which was responsible for the building of the Basilica di San Petronio and the Loggia dei Mercanti, alternated with Papal or Visconti resurgences, while the city's families engaged in continual internecine fighting.
Early modern
In 1337, the rule of the noble Pepoli family, nicknamed by some scholars as the "underground nobles" as they governed as "the first among equals" rather than as true nobles of the city. This noble family's rule was in many ways an extension of past rules, and resisted until March 28, 1401 when the Bentivoglio family took over. The Bentivoglio family ruled Bologna, first with Sante (1445–1462) and then under Giovanni II (1462–1506). This period was a flourishing one for the city, with the presence of notable architects and painters who made Bologna a true city of art. During the Renaissance, Bologna was the only Italian city that allowed women to excel in any profession. Women had much more freedom than in other Italian cities; some even had the opportunity to earn a degree at the university. The School of Bologna of painting flourished in Bologna between the 16th and 17th centuries, and rivalled Florence and Rome as the center of painting.
Giovanni's reign ended in 1506 when the Papal troops of Julius II besieged Bologna and sacked the artistic treasures of his palace. From that point on, until the 18th century, Bologna was part of the Papal States, ruled by a cardinal legato and by a
