The local economy of Neemuch is mainly based on the agriculture produce market (called Krishi Upaj Mandi in local Hindi language) which is Asia's largest production mandi and world's Second largest as per 2011 repot by MCX & WTO for agri product. Some of the crops traded in the agriculture market of Neemuch are garlic, groundnut, soybeans, wheat, corn, and different types of pulses. Neemuch has many cooking oil mills.
Neemuch district is one of the largest producers of opium in the country. Neemuch also has one of the only two opium factories in India. The climate of Neemuch district is apt for the production of opium and thus the opium trade is one of the major occupations in the region. Neemuch also has one of the only one isabgol husk plant in MP. The climate of neemuch district is apt for the production of isabgol(psyllium seed)
