Madikeri is well connected by road with Mangalore, Hassan, Mysore, Bangalore and Kannur, Thalassery, and Wayanad of neighbouring state Kerala. There are three Ghat roads for reaching Kodagu from coastal regions of Kerala and Karnataka: the Sampaje–Madikeri Ghat road from Mangalore, the Panathur–Bhagamandala Ghat road from Kasaragod, Kanhangad, Malom and chittarikkal and the Makutta–Perumbadi/Virajpet Ghat road from Kannur and Thalassery.
The nearest railway stations are Thalassery and Kannur in Kerala and Mangalore, Mysore and Hassan are the nearest in Karnataka.
The nearest airports are at Mysore and Mangalore. Mysore Airport is at a distance of 130 km from Madikeri and 115 kilometres (71 mi) from Virajpet. Mangalore International Airport is located 140 kilometres (87 mi) from Madikeri and 172 kilometres (107 mi) from Virajpet.
The nearest seaport for Kodagu is New Mangalore Port at Panambur in Mangalore, 145 kilometres (90 mi) from Madikeri
