Santa Cruz del Quiché was founded by Pedro de Alvarado, a companion and second in-command of conquistador Hernán Cortés, after he burned down the nearby Maya capital city of Q'umarkaj (or Utatlán, in the Nahuatl language). The oldest buildings, including a largecathedral and clock tower in the central plaza, were constructed out of the stones of the Q'umarkaj ruins by the Dominicans. Some think it likely that it was in Santa Cruz where a group of anonymous K'iche' nobles of the Nim Ch'okoj class transcribed the Popol Vuh, thesacred text of the Maya.
In Santa Cruz, the former rulers of Q'umarkaj were reduced to the status of peasant. As the living conditions were so pitiful in the city, the town of Santo Tomás Chichicastenango, about 20 miles to the south of Santa Cruz, began to swell with the immigration of displaced Mayas and soon passed up Santa Cruz in both size and importance.
