The nearest airports to Quedlinburg are Hannover 120 km north-west, and Leipzig/Halle Airport 90 km south-east. Much closer, but only served by a few airlines, is Magdeburg-Cochstedt. At Ballenstedt-Assmussstedt a airfield is located for general aviation.
Regional trains run on the standard gauge Magdeburg�Thale line by Deutsche Bahn and the private company Connex connect Quedlinburg with Magdeburg, Thale and Halberstadt.
In 2006 the Selke Valley branch of the Harz Narrow Gauge Railways was extended into Quedlinburg from Gernrode, giving access to the historic steam narrow gauge railway, Alexisbad and high Harz plateau.
Quedlinburg is connected by regional buses to the surrounding villages and small towns.
Additionally there are also buses to Berlin, run by the company Berlin Linien Bus
