Valley International Airport (HRL / KHRL) has domestic flights from Harlingen, Texas and is 43 miles from South Padre Island.
McAllen Miller International Airport is served by American, United, and Allegiant Air.
Car
Texas State Route 100 connects South Padre Island to the city of Port Isabel on the mainland, and continues on to meet US Route 77/83 between Harlingen and Brownsville. Texas State Route 48 links Port Isabel with Brownsville. If you will be landing at McAllen Miller International Airport, US Route 83 directly connects the airport to Texas State Route 100, passing through Harlingen en route.
Bus
Catch the $2 Rio Transit bus from downtown Brownsville to its last stop in Port Isabel, and catch the free Wave from there. The Wave runs every half hour and takes you all over South Padre as far as the Visitors Center on the north end.
Boat
There are no ferry boat services, but if you have your own boat, just point yourself to the place on the Gulf of Mexico where Texas meets Mexico and you're at South Padre Island! There are several marinas both on South Padre and at Port Isabel.
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