As of 2007, Kreuzlingen had an unemployment rate of 3.54%. As of 2005, there were 92 people employed in the primary economic sector and about 20 businesses involved in this sector. 2,799 people are employed in the secondary sector and there are 183 businesses in this sector. 6,042 people are employed in the tertiary sector, with 821 businesses in this sector. In 2000 there were 11,275 workers who lived in the municipality. Of these, 3,510 or about 31.1% of the residents worked outside Kreuzlingen while 4,725 people commuted into the municipality for work. There were a total of 12,490 jobs (of at least 6 hours per week) in the municipality. Of the working population, 8.4% used public transportation to get to work, and 48.2% used a private car.
Earlier, the majority of the inhabitants made a living in the wine industry. However, because of diseases and bad harvests, the last wine grapes were raised in Kreuzlingen in 1938.
Today, the local economy is largely commercial and manufacturing, with the largest employer being a clothing manufacturer
