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Most of the major rental car companies have outlets at Piazzale Roma, at the edge of the city. These are on the ground floor of one of the major parking stations. When you are dropping off your car, you need to find street parking and then walk to the rental car outlet and hand in the keys. Do not park in the parking station! There is a vaporetto stop across the road from the parking station.
By bus
There is a direct bus between Marco Polo airport and the Piazzale Roma, on the west bank of Venice operated by ATVO . Starts twice an hour, takes 20 minutes and costs €5. The Piazzale Roma bus station is well served by vaporetti and water-taxis ... and of course, you can walk everywhere. From Mestre, you can take a bus to Venezia- Piazzale Roma. the ticket is €1.30 but if you buy it in the bus it will cost €2.50. You can buy bus tickets from specialized ticket kiosks and vending machines, as well as tobacconists and newsstands. All of the city is connected to Venice by bus.
By boat
Ships arrive at the Stazione Marittima which is at the west end of the main islands, it is served by vaporetti and water taxis
