Americas
• Ioannis Kondylakis (1862–1920) author
• Vitsentzos Kornaros (1553–1613) author
• Stephanos Sahlikis (1330-after 1391) poet
• Lili Zografou (1922–1998) author
Scientists and Scholars
Marcus Musurus (left) and Nicholas Kalliakis (right) were two significant Renaissance humanists, scholars and philosophers from Heraklion.
• Nicholas Kalliakis (1645–1707)- Greek Cretan scholar and philosopher
• Andreas Musalus (ca. 1665–1721) Greek Cretan professor of Mathematics, Philosopher and Architectural theorist
• Francesco Barozzi (1537–1604) mathematician and astronomer
• Manolis Hatzidakis, archaeologist
• Fotis Kafatos biologist, President of the European Research Council
• Maximos Margunios (1549–1602) scholar, theologian, poet and writer, titular bishop of Kythira
• Marcus Musurus (Markos Mousouros) (1470–1517) scholar and philosopher
• Nikolaos Panagiotakis (1935–1997) byzantinologist
• Peter of Candia also known as Antipope Alexander V, philosopher and scholar.
• Joseph Sifakis (1946–present) computer scientist, co-recipient of the 2007 Turing Award
• Michael N. Katehakis (1952–present) applied mathematician and operations research Rutgers University
• Gerasimos Vlachos (1607–1685), scholar
• Simone Stratigo (ca. 1733–1824), Greek mathematician and an Nautical science expert, whose family was from Heraklion (Candia), Crete.
Painting
El Greco (Dominikos Theotokopoulos).
• Theophanes (ca