Fray Pedro de Alcal� founded the town in 1716 as Indian missionary town. The first inhabitants were 73 families from the Atures tribe. There were also Indians from the Cherrecheres, Guamonteyes, Guamos, Colorados, Achaguas, Gu�ricos, Gayones and Otomaco and Taparita groups. A year after the foundation most settlers died from an epidemic.
Fray Diego de Urbique refounded Sarare in 1754 as the Mission of Saint Nicolas of Sarare
