as some of the first settlers of New Amsterdam) lived (and operated a printing press) for a time in the early 17th century before their departure to Massachusetts and New Amsterdam in the New World.
In the 17th century, Leiden prospered, in part because of the impetus to the textile industry by refugees from Flanders. While the city had lost about a third of its 15,000 citizens during the siege of 1574, it quickly recovered to 45,000 inhabitants in 1622, and may have come near to 70,000 circa 1670. During the Dutch Golden Era, Leiden was the second largest city of Holland, after Amsterdam.
From the late 17th century onwards Leiden slumped, mainly due to the decline of the cloth industries. In the beginning of the 19th century the baize manufacture was altogether given up, although industry remained central to Leiden economy. This decline is painted vividly by the fall in population. The population of Leiden had sunk to 30,000 between 1796 and 1811, and in 1904 was 56,044.
From the 17th to the early 19th century, Leiden was the publishing place of one of the most important contemporary journals, Nouvelles Extraordinaires de Divers Endroits, known also as Gazette de Leyde.
19th and 20th century
On 12 January 1807, a catastrophe struck the city when a boat loaded with 17,400 kg of gunpowder blew up in the middle of Leiden. 151 persons were killed, over 2000 were injured and some 220 homes were destroyed. King Louis Bonaparte personally visited the city to provide assistance to the victims. Although located in the center of the city, the area destroyed remained empty for many years. In 1886 the space was turned into a public park.
In 1842, the railroad from Leiden to Haarlem was inaugurated and one year later the railway to Den Haag was completed, resulting in some social and economic improvement. Perhaps the most important piece of Dutch history contributed by Leiden was the Constitution
