According to CBS, as of 2000, in the city there were 4,980 salaried workers and 301 are self-employed. The mean monthly wage in 2000 for a salaried worker in the city is ILS 4,200, a real change of 3.3% over the course of 2000. Salaried males have a mean monthly wage of ILS 5,314 (a real change of 5.1%) versus ILS 2,998 for females (a real change of -1.0%). The mean income for the self-employed is 6,106. There are 470 people who receive unemployment benefits and 1,409 people who receive an income guarantee.
Beit She'an is a center of cotton-growing, and many of residents are employed in the cotton fields of the surrounding kibbutzim. Other local industries include a textile mill and clothing factory
