Clovis I (c. 466–511) and the Visigoths signed a peace treaty of alliance with the Arvernians in 503, which assisted him in his defeat of the Visigothic kingdom in the Battle of Vouillé in 507.
Joan of Arc passed through in 1426 on her way to Orleans to the Battle of Patay.
The Amboise conspiracy was the conspiracy of Condé and the Huguenots in 1560 against Francis II, Catherine de' Medici, and the Guises.
The Edict of Amboise (1563) conceded the free exercise of worship to the Protestants.
The chateau at Amboise was home to Mary Stewart, Queen of Scots for much of her early life, being raised there at the French court of Henry II. She arrived in France from Scotland in 1548 aged six, via the French King's favourite palace at Saint Germain en Laye near Paris, and remained in France until 1561, when she returned to her homeland - sailing up the Firth of Forth to Scotlands Capital, Edinburgh, on 15 August that year.
The great Leonardo da Vinci spent the last years of his life in Amboise. Some of his inventions are still there and have not been removed. The house has lost some of its original parts, but it still stands today and has a beautiful overlook of the Loire River.
Here was born in 1743 – Louis Claude de Saint-Martin French philosopher, known as Le Philosophe Inconnu. (d. 1803).
Abd el Kader Ibn Mouhi Ad-Din (c. 1807–83) was imprisoned at the Château d'Amboise
