The Cafayates were a tribe of the Diaguita-Calchaquí group, which, together with the related Tolombón, inhabited the Valles Calchaquíes prior to the arrival of the Spanish Conquistadores. Their language was known as Cacán. Like other Diaguita tribes, they had recently fallen under the influence of the Incas, after a prolonged resistance. They later mounted a fierce resistance to the Spaniards.
Even though most agree that the root of Cafayate is Quechua, the meaning of the term is disputed. Some claim it to mean "Box of Water", others to be a deformation of Capac-Yac ("Great Lake") or Capac-Yaco ("Great Chief" or "Wealthy People"). Another Cacánversion understands it as "Grave of Sorrows"
